ECTS - University of Pisa
The student will acquire knowledge about the computational chemistry applied to the biological and chemical field
The assessment of knowledge will be the subject of the evaluation of the written/oral exam.
The student who completes the course successfully will be able to demonstrate a solid knowledge of the advanced understanding of ligand-protein and protein-protein interactions. He/she will be familiar with a broad range of ligand- and structure-based computational methods and finally he/she will be able to perfom computational modeling tasks using state of the art software
The student will have to answer the questions that will be proposed in the exam
During the lab sessions, the accuracy and precision of the activities carried out will be evaluated
Basis of biology and chemistry.
Delivery: face to face
Teaching methods:
The course aims to provide the basic elements of in silico modeling of biological and physio-pathological systems. In particular, the course will deal with the objectives and tools for the formulation of theoretical models, the computational techniques for their simulation and for parameters identification using experimental data. Specifically, the course will focus on in silico models for protein analysis, basic in silico drug-design techniques and chemometric analyses able to support in vivo toxicity studies. The main objective is to provide the student with conceptual and operational tools that allow him/her to develop the entire modeling process for some significant biomedical applications.
Module "Bioinformatics": learning materials and video recordings of lectures are made available on the MS Teams group for the course (link).
Module "In-silico Models": There are not recommended readings. The teacher will supply the material during the lessons.
MS Teams group for the course (link).
