ORGANIC NATURAL SUBSTANCES OF BIOLOGICAL AND APPLICATIVE INTEREST
Academic year2016/17
CourseCHEMISTRY
Code208CC
Credits6
PeriodSemester 2
LanguageItalian
| Modules | Area | Type | Hours | Teacher(s) |
| SOSTANZE ORGANICHE NATURALI DI INTERESSE BIOLOGICO E APPLICATIVO | CHIM/06 | LEZIONI | 48 | |
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Knowledge
The student who completes the course successfully will be able to demonstrate a solid knowledge of the main issues related to the metabolic pathways discussed throughout the course, with particular attention to their chemical and biosynthetic aspects. Moreover, he or she will acquire knowledge on many important classes of biologically active and medicinally or agronomically useful natural compounds, or their analogues. Lastly, beyond the mere acquisition of chemical and biochemical knowledge and skills, he or she will develop a mindset and a mental elasticity that can enable them to easily understand biological and pharmacological questions, as well as interact with experts in these areas.
Assessment criteria of knowledge
During the oral exam the student must be able to demonstrate his/her knowledge of the course material and be able to discuss the matter thoughtfully and properly.
Methods:
Teaching methods
Delivery: face to face
Learning activities:
- attending lectures
- individual study
Attendance: Advised
Teaching methods:
Syllabus
The course aims to give students tools for the understanding and the interpretation, from a chemical point of view, of some important aspects of the secondary metabolism, essential for the life. In particular, after an introduction to the main biosynthetic building blocks and reactions, some important biogenetic pathways will be examined in detail: the acetate pathway, the scikimate pathway and the mevalonate (and methylerythritol phosphate) pathway. Moreover, information will be supplied on the bioactivity, the natural sources and the possible uses of metabolites of greater biological and applicative interest. Emphasis will be given to physiologycally, medicinally or agronomically important natural substances, or their analogues.
Bibliography
Required reading include:
- P. M. Dewick "Medicinal Natural Products. A Biosynthetic Approach", 3rd Edition, John Wiley & Sons Ltd, 2009.
- The copies of the exhaustive slides shown during the lectures.
Further bibliography will be indicated in the above mentioned slides and during lectures.
Updated: 14/11/2016 17:27
