The main goal of this course is to show the most recent protocols for the synthesis, from lab-scale to industrial-scale, of relevant classes of organic compounds including biologically-active derivatives, agrochemicals and new materials. Among these protocols, main enphasis will be given to the metal-mediated carbon-carbon and carbon-heteroatom bond formation reactions, starting from the classical procedures involving organometallic derivatives to the most innovative, such as carbon-hydrogen or carbon-heteroatom activation reactions. Practical and mechanistic aspects of the examined synthetic protocols will be critically discussed.
A further goal of the course will be to illustrate the basics of physical organic chemistry, in particular concerning the rationalization of the reactivity and properties of organic compounds. By using this approach, applications of conjugated organic molecules in the field of organic electronics will be discussed.