The course aims at providing students with solid background on Multimedia Information Retrieval, Content-Based Retrieval, Similarity Search, Computer Vision, Multimedia Data Mining, leveraging on solutions coming from Artificial Intelligence. Students will understand the challenges and issues related to effectiveness, efficiency, and scalability when dealing with very large (web scale) multimedia collections. The course will cover issues and solutions to Similarity Search, Multimedia Content-Based Retrieval, Object Detection and Recognition, Multimedia Content Analysis and De-scription, Multimedia Content-Based Indexing, Multimedia Data Mining and Classification, Text Retrieval, Audio retrieval, Scalable Access Methods for Similarity Searching, Deep Learning tech-niques applied to multimedia.