The course aims to broaden the student's skills on purification, analysis and structural characterization techniques applied to the development of original small-molecules with potential evolution as new drugs. Specifically, the student will be able to acquire skills regarding the chemical-physical (extraction, distillation, crystallization) and chromatographic techniques useful for the treatment of complex mixtures deriving from synthetic protocols, for the isolation and purification of the compounds obtained, for the determination of their purity degree, as well as to deepen the knowledge of spectroscopic techniques (NMR, MS) useful for their structural characterization. An additional level of knowledge will concern the acquisition of useful skills for the critical management of problems in the experimental analytical field.