ECTS - University of Pisa
Corso Integrato di Patologia Sistematica II
CORE CURRICULUM
MODULO DI MALATTIE INFETTIVE
MODULO DI PARASSITOLOGIA
MODULO DI MICROBIOLOGIA CLINICA
MODULO DI DERMATOLOGIA
Infectivology, Parasitology and Clinical Microbiology The student will demonstrate a solid knowledge of the main diagnostic procedures and clinical aspects for human infections and diseases caused by bacteria, fungi, viruses and parasites. Dermatology and Venereology Learning outcomes The student who completes the course successfully will demonstrate a solid knowledge of the clinical and diagnostic procedures for skin and venereal diseases (inflammatory, neoplastic, infective). He or she will acquire knowledge of the pathogenetic mechanisms of the skin and venereal diseases and the principles of their management. Lastly, he or she will be aware of modern approaches of laboratory diagnosis of skin and venereal diseases that rely on conventional office based procedures and molecular and biotechnological approaches. He or she will also acquire knowledge on the fundamentals of the non invasive diagnostic tests on skin samples able to explore organ functionality.
Per i moduli di Malattie Infettive, di Parassitologia, di Microbiologia Clinica e di Dermatologia la prova è tramite quiz ed esame orale.
The student will be assessed, by an oral exam, on his/her ability to discuss the main course contents using the appropriate terminology. During the exam, the student must be able to demonstrate his/her knowledge of the course issues and be able to present and discuss correctly the main diagnostic procedures presented during the course. The student must demonstrate the ability to discuss, with critical awareness, issues relative to infectivology and parasitology, clinical microbiology,skin and venereal diseases. The student must demonstrate the ability to put into practice and to execute, with critical awareness, the activities illustrated or carried out under the guidance of the teacher during the course.
Methods:
Corso di Microbiologia
Corso di Patologia Generale (modulo di Immunologia)
Delivery: face to face
Learning activities:
Attendance: Mandatory
Teaching methods:
MODULO DI MICROBIOLOGIA CLINICA
1. Rapporto ospite-parassita: simbiosi, parassitismo, opportunismo. Contaminazione, colonizzazione, infezione, malattia. Infezione endogena, esogena, nosocomiale.
2. Modalità di raccolta, trasporto e trattamento del materiale biologico per la diagnosi batteriologica.
3. Tampone faringeo.
4. Espettorato e valutazione della qualità dell’espettorato.
5. Urinocoltura. Tampone uretrale.
6. Coprocoltura. Terreno di arricchimento.
7. Emocoltura. Interpretazione dei risultati di emocoltura positiva.
8. Coltura del liquor. Esami diagnostici rapidi.
9. Identificazione microbica classica e tramite MALDI-TOF.
10. Saggio di suscettibilità antimicrobica e sua interpretazione.
11. Esame sierologico: test di agglutinazione, precipitazione, neutralizzazione.
12. Tipizzazione molecolare.
MODULO DI MALATTIE INFETTIVE
MODULO DI PARASSITOLOGIA
MODULO DI DERMATOLOGIA
1. Fisiologia della cute e lesioni dermatologiche elementari primitive e secondarie
2. Diagnostica delle malattie cutanee
3. Acne e dermatite seborroica
4. Dermatosi parassitarie, batteriche, micotiche e virali
5. Dermatosi bollose
6. Dermatite atopica e Eczemi
7. Orticaria- angioedema. Eritemi polimorfo-reazioni cutanee da farmaci
8. Dermatiti da contatto, allergiche e irritative
9. Psoriasi
10. Le Eritrodermie primitive e secondarie
11. Malattie del connettivo: Lupus eritematoso, Dermatomiosite e Sclerodermie
12. Genodermatosi
13. Idrosadenite suppurativa
14. Vasculiti e vasculopatie
15. Ulcere cutanee e riparazione tessutale
16. Ustioni
17. Precancerosi cutanee e tumori cutanei benigni
18. Nevi e Melanomi
19. Tumori cutanei maligni, linfomi e pseudolinfomi cutanei
20. Nozioni di dermatologia chirurgica e fisioterapia dermatologica
21. Manifestazioni cutanee nelle Malattie Sessualmente Trasmesse
22. Malattie degli annessi cutanei
23. Principali dermatosi dell'età pediatrica
CLINICAL MICROBIOLOGY MODULE
1. Host-parasite relationship: symbiosis, parasitism, opportunism. Contamination, colonization, infection, disease. Endogenous, exogenous, nosocomial infection. 2. Methods of collection, transport and treatment of biological material for bacteriological diagnosis. 3. Throat swab. 4. Sputum and assessment of sputum quality. 5. Urine culture. Urethral swab. 6. Coproculture. Enrichment ground. 7. Blood culture. Interpretation of positive blood culture results. 8. CSF culture. Rapid diagnostic tests. 9. Classical and MALDI-TOF microbial identification. 10. Antimicrobial susceptibility test and its interpretation. 11. Serological test: agglutination, precipitation, neutralization test. 12. Molecular typing.
INFECTIOUS DISEASES FORM
1. Pathomorphosis of infectious diseases. 2. Principles of epidemiology of infectious diseases. 3. Innate and adaptive defense mechanisms against infections. 4. The clinical approach to the patient with fever with or without organ symptoms. 5. Bacteremia, sepsis, septic shock. 6. HIV and AIDS infection: epidemiology, clinical and instrumental diagnostics, therapeutic approach. 7. Infections of the respiratory system: epidemiology, clinical and instrumental diagnostics, therapeutic approach. 8. Gastrointestinal infections including viral hepatitis: epidemiology, clinical and instrumental diagnostics, therapeutic approach. 9. Urinary tract infections: symptomatic and asymptomatic bacteriuria, bacterial pyelonephritis, prostatitis and urethritis: epidemiology, clinical manifestations and therapeutic approach. 10. Infective endocarditis: epidemiology, clinical and instrumental diagnostics, therapeutic approach. 11. Infections of the central nervous system (meningitis and neurasites) and peripheral nervous system: epidemiology, clinical and instrumental diagnostics, therapeutic approach. 12. Lyme disease. 13. Button fever and other tick-borne infections. 14. Brucellosis: epidemiology, clinical manifestations, therapeutic approach. 15. Abdominal typhus and salmonellosis: epidemiology, clinical manifestations, therapeutic approach. 16. Pulmonary and extrapulmonary tuberculosis: epidemiology, clinical and instrumental diagnostics, therapeutic approach. 17. Listeriosis and leptospirosis: epidemiology, clinical manifestations, prevention and therapeutic approach. 18. Nosocomial infections: epidemiology, clinical and instrumental diagnostics, prevention and therapeutic approach.
MODULE OF PARASITOLOGY 1. Parasitosis as a public health problem on a global, European and Italian level. 2. Malaria: epidemiological, biological, diagnostic and clinical aspects, chemoprophylaxis. 3. Babesiosis: epidemiological, biological, diagnostic and clinical aspects 4. Toxoplasmosis: epidemiological, biological, diagnostic and clinical aspects. 5. Cutaneous and visceral leishmaniasis: epidemiological, biological, diagnostic and clinical therapeutic aspects. 6. Trichomoniasis: epidemiological, biological, diagnostic and clinical aspects. 7. Giardosis: epidemiological, biological, diagnostic and clinical therapeutic aspects. 8. Intestinal and extraintestinal amoebiasis: epidemiological, biological, diagnostic and clinical aspects. 9. Cystic and alveolar echinococcosis: epidemiological, biological, diagnostic and clinical therapeutic aspects. 10. Teniasis and neurocysticercosis: epidemiological, biological, diagnostic and clinical therapeutic aspects. 11. Ascaridiosis, toxocarosis and anisakidosis: epidemiological, biological, diagnostic and clinical aspects. 12. Strongyloidosis: epidemiological, biological, diagnostic and clinical aspects. 13. Intestinal and urinary schistosomiasis: epidemiological, biological, diagnostic and clinical aspects. 14. Filariasis: epidemiological, biological, diagnostic and clinical therapeutic aspects. MODULE OF DERMATOLOGY 1. Physiology of the skin and primary and secondary elementary dermatological lesions 2. Diagnosis of skin diseases 3. Acne and seborrheic dermatitis 4. Parasitic, bacterial, fungal and viral dermatoses 5. Bullous dermatosis 6. Atopic Dermatitis and Eczema 7. Urticaria - angioedema. Polymorphic erythema-drug skin reactions 8. Contact, allergic and irritative dermatitis 9. Psoriasis 10. Primitive and secondary erythroderma 11. Diseases of the connective tissue: Lupus erythematosus, Dermatomyositis and Scleroderma 12. Genodermatosis 13. Hidradenitis suppurativa 14. Vasculitis and vasculopathies 15. Skin ulcers and tissue repair 16. Burns 17. Precancerous skin and benign skin tumors 18. Nevi and Melanomas 19. Malignant skin tumors, lymphomas and cutaneous pseudolymphomas 20. Notions of surgical dermatology and dermatological physiotherapy 21. Skin manifestations in sexually transmitted diseases 22. Diseases of the skin appendages 23. Main pediatric dermatoses
TESTO CONSIGLIATO
MORONI M., ESPOSITO R., DE LALLA F.: “Manuale di malattie infettive”, 8ª ed, Masson, 2014.
TESTO DI CONSULTAZIONE
MANDELL, DOUGLAS, BENNETT: “Principles and Practices of Infectious Disease”, 8th ed., 2014.
CAINELLI, GIANNETTI, REBORA,: "Manuale di Dermatologia Medica e Chirurgica" 6th ed., 2016
TESTO DI APPROFONDIMENTO
DE CARNERI Parassitologia Medica e Diagnostica parassitologica, Brandonisio O., Bruschi F., Genchi C., Pozio E. CEA, 2013.
CANCRINI G. Parassitologia medica illustrata. III Ed. Edra, Milano, 2017.
Most up-to-date textbooks of Clinical Microbiology and Infectious Diseases are suitable for the aim of the course; advised textbook(s) and bibliography will be indicated. Additional didactic material and recommended readings will be provided by the teacher(s). Most up-to-date textbooks of General Dermatology and Colour Atlas of Skin Diseases are suitable for the aim of the course; advised textbook(s) and bibliography will be indicated. Additional didactic material and recommended readings will be provided by the teacher(s).
DE CARNERI Parassitologia Medica e Diagnostica parassitologica, Brandonisio O., Bruschi F., Genchi C., Pozio E. CEA, 2013.
CANCRINI G. Parassitologia medica illustrata. III Ed. Edra, Milano, 2017.
Prova scritta con 45 quiz a risposta multipla, che dà l'accesso alla prova orale che mira a verificare l'effettiva conoscenza degli argomenti del programma.
Written test with 45 multiple choice quizzes, which gives access to the oral test which aims to verify the actual knowledge of the program topics.
RICEVIMENTO STUDENTI
I docenti ricevono su appuntamento preso via e-mail o per telefono.
