Lo studente avrà acquisito conoscenze in merito agli strumenti e alle metodologie attualmente utilizzate per valutare, con un approccio scientificamente valido, l'effetto benefico di alimenti e loro componenti sulla salute umana.
The student will have acquired knowledge about the tools and methodologies currently used to evaluate, with a scientifically valid approach, the beneficial effect of foods and their components on human health.
Per l'accertamento delle conoscenze sarà svolta una prova in itinere utilizzando un test per valutare l'apprendimento degli studenti sulla prima parte delle lezioni frontali.
For the assessment of knowledge, an ongoing test will be carried out using a test to evaluate students' learning on the first part of the lectures.
Al termine del corso lo studente sarà in grado di valutare criticamente l'utilizzo e l'efficacia di un nutraceutico.
At the end of the course the student will be able to critically evaluate the use and effectiveness of a nutraceutical.
Lo studente potrà selezionare un articolo di interesse, tra quelli forniti a lezione, ed acquisire tecniche di analisi durante le esercitazioni per sviluppare un approccio critico allo studio di un nutraceutico.
The student will be able to select an article of interest, among those provided in class, and acquire analysis techniques during the exercises to develop a critical approach to the study of a nutraceutical.
Saranno acquisite le conoscenze necessarie per valutare la validità di un nutraceutico sia da un punto di vista sperimentale che legislativo.
The necessary knowledge will be acquired to evaluate the validity of a nutraceutical both from an experimental and a legislative point of view.
Durante le esercitazioni saranno verificate le modalità di analisi utilizzate nella valutazione di un nutraceutico.
During the exercises the analysis methods used in the evaluation of a nutraceutical will be verified.
Cenni di genetica e biologia molecolare
Chimica generale e degli alimenti
Nutraceutica e nutrigenomica
Cenni di patologia
Elements of genetics and molecular biology
General chemistry and food chemistry
Nutraceutical and nutrigenomics
Outline of pathology
Lezioni frontali
Esercitazioni :
Frontal lessons Definition of nutraceutical: outline of Italian and European legislation. The importance of microbiota: prebiotics and probiotics. Main mechanisms of action of food or food extracts; notes on the epigenetics of nutrition. New biotechnologies to improve food quality: fermentation and use of mycorrhizae. Analysis of the properties of cereals fermented and study of the properties of "symbiotic" or "sulfite 0" wines. From chemical characterization to clinical study: use of in vivo experimental models in nutraceutical research. Nutraceutical applied in vivo on spontaneous and induced and in vitro pathologies on human microbiota models Bioactive molecules in animal-derived products. Laboratory exercises: Preparation of solutions used in the analysis of a nutraceutical; notes on instrumentation (3h) Fermentation and analysis of fermented products (3h) Characterization of an extract (3h) Evaluation of polyphenols / antioxidant capacity (3h)
Verranno fornite slide e riferimenti bibliografici durante il corso. Verranno forniti articoli scientifici da scegliere per la discussione in sede di esame.
Slides and references will be provided during the course. Scientific articles will be provided to be chosen for discussion during the examination.
Gli studenti non frequentanti troveranno le diapositive delle lezioni/esercitazioni su e-learning, dovranno procurarsi un articolo scientifico su tematiche attinenti al corso e potranno contattare i docenti per ulteriori chiarimenti.
Non-attending students will find slides of lessons/exercises on e-learning, they will have to obtain a scientific article on topics related to the course and will be able to contact the teachers for further clarifications.
Per presentarsi all'esame è utile, ma non necessario, superare la prova in itinere. Si consiglia di seguire le esercitazioni essendo oggetto delle domande di esame.
The exam consists of an oral test. It will be possible to take a written test in quiz, in itinere test, on the first part of the program. The in itinere test takes place in a classroom and has a duration of 1 hour. The result remains valid for more than one appeal. The ongoing test is passed if the correct answers exceed 60%. The oral exam consists of an interview between the candidate and the two professors who hold the course on the topics covered in class. Students will also be required to display a scientific article of their choice on the topics covered during the lessons. The average duration of the interview will be around 30 minutes, based on the result of the trial in itinere. The oral exam will not be passed if the candidate shows he is not able to express himself clearly or if the candidate does not correctly answer at least the questions corresponding to the most basic part of the course To present yourself for the exam it is useful, but not necessary, to pass the test in progress. It is advisable to follow the exercises being the subject of the exam questions.