CdSFISICA
Codice124BB
CFU6
PeriodoSecondo semestre
LinguaItaliano
The student who successfully completes the course will have the ability to understand the principles of Nuclear Magnetic Resonance and its application in living systems; will be able to demonstrate the knowledge of electromagnetic radiation interaction with living systems and the techniques for acquiring images and to evaluate T1 and T2 relaxation effects; will be able to demonstrate knowledge on the realization of basic coils for signal detection; will be aware of the power and pitfalls of the advanced techniques for quantitative measurements.
During the oral exam the student must be able to demonstrate his/her knowledge of the course material and be able to discuss the principles and methods with appropriate terminology. The student will be assessed on his/her demonstrated ability to put into practice and to execute, with critical awareness, the activities illustrated or carried out during the laboratory.
Methods:
- Final oral exam
- Laboratory report
Further information:
final oral exam 60%; laboratory report 40%
Delivery: face to face
Learning activities:
- attending lectures
- participation in seminar
- Laboratory work
Attendance: Mandatory
Teaching methods:
- Lectures
- Seminar
- laboratory
Classical Bloch equations and basic quantum mechanical description Magnetization Interaction with RF; rotating frame Receiving and acquiring data Simple sequences to measure relaxation times; Gradient echo, spin echo and stimulated echo, inversion recovery Reconstruction imaging: slice selection, Phase and Frequency encoding (k space) Basic spectroscopy, and advanced imaging techniques Components of an MR scanner Interactions of MR fields with biological tissues
Recommended reading: [1] Magnetic Resonance Imaging: Physical Principles and Sequence Design. E.M Haacke, R W. Brown, M.R. Thompson, R. Venkatesan. Ed Wiley-Liss, 1999. Further bibliography [2] In Vivo NMR Spectroscopy: Principles and Techniques. Robin A. de Graaf. Ed. John Wiley & Sons, 2013. [3]Quantitative MRI of the Brain: Measuring Changes Caused by Disease. Paul Tofts. Ed. John Wiley and Sons, 2003. [4] Ultra High Field Magnetic Resonance Imaging. Pierre-Marie Robitaille, Lawrence Berliner. Ed. Springer, 2007.