Academic year2016/17
CourseDENTISTRY AND DENTAL PROSTHODONTICS
Code237EE
Credits9
PeriodSemester 1
LanguageItalian
| Modules | Area | Type | Hours | Teacher(s) |
| BIOCHIMICA | BIO/10 | LEZIONI | 60 | |
| BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICA | BIO/12 | LEZIONI | 10 | |
| BIOLOGIA MOLECOLARE | BIO/11 | LEZIONI | 20 | |
Obiettivi di apprendimento
Knowledge
The student will be able to demonstrate a solid knowledge of each field of Biochemistry, stimulated by new experimental findings and new insights.
The student will be able to demonstrate the recognition of the principles of the energy transfer in cells, the mechanisms by which the major metabolic pathways are regulated.
The student will be able to demonstrate advanced knowledge of many applications of Biochemistry to problems of human health and disease.
For the principles of Molecular Biology, students will have to acquire in depth knowledge of pioneering discoveries on DNA, RNA, protein synthesis and the concept of "gene". Experimental findings leading to breakthroughs in recombinant DNA, transposons and recombination, molecular embryology and immnunology, genomics and molecular carcinogenesis will be presented and are expected to become solid background knowledge for students of these classes.
Assessment criteria of knowledge
The student will be assessed on his/her demonstrated ability to discuss the main contents using the appropriate terminology.
For molecular biology (BM), particular emphasis will be placed on the experimental evidence leading to BM principles (evidence based medicine).
Methods:
Further information:
Biochemitry 65%
Molecular Biology 25%
Clinical Biochemistry 10%
Modalità di verifica dei comportamenti
Firma foglio di presenza a lezione
Prerequisiti (conoscenze iniziali)
Chimica generale ed organica
Teaching methods
Delivery: face to face
Learning activities:
- attending lectures
- participation in discussions
- individual study
Attendance: Mandatory
Teaching methods:
- Lectures
- Task-based learning/problem-based learning/inquiry-based learning
Syllabus
Proteins: three dimensional conformation. Collagen. Lipids and lipoproteins. Sugars: disaccharides and polisaccharides.
Enzymes: kinetics and enzyme inibition. The Michaelis- Menten equation. Alloteric enzymes. Isoenzymes.Vitamins and coenzymes.
Catabolism and anabolism. Glycolisis. Oxidation of pyruvate to Acetil-CoA. The tricarboxilic acid cycle and the compartimentation of respiratory metabolism. Lactate dehydrogenase. Gluconeogenesis. Synthesis and breakdown of glycogen.
Metabolism of lipids: beta-oxidation of fatty acids. Glycoproteins. Cholesterol.
Metabolism of protein. Transamination. Oxidative deamination. Urea cycle. Decarboxilation of amino acid.
Bibliografia e materiale didattico
Nelson and Cox, I principi di Biochimica di Lehninger VI ed
Lucidi delle lezioni
Bibliography
J.Tymoczko, J. Berg, L. Stryer- Principi di Biochimica. Zanichelli Ed.
Siliprandi e Tettamanti- Biochimica Medica. Piccin Ed.
J.D. Watson, Caudy, Meyers and Witowski: DNA Ricombinante Ed. Zanichelli, 2008.
R. Weinberg: The biology of CANCER Garland Science, Taylor and Francis, 2014.
Modalità d'esame
Esame scritto con prova in itinere
Updated: 14/11/2016 17:27
