MASS SPECTROMETRY IN ORGANIC AND BIOORGANIC CHEMISTRY
Academic year2016/17
CourseCHEMISTRY
Code104CC
Credits3
PeriodSemester 1
LanguageItalian
| Modules | Area | Type | Hours | Teacher(s) |
| SPETTROMETRIA DI MASSA IN CHIMICA ORGANICA E BIOORGANICA | CHIM/06 | LEZIONI | 24 | |
Programma non disponibile nella lingua selezionata
Knowledge
The course is an introduction to mass spectrometry and its applications in different fields. The student who complete the course will know what is mass spectrometry and will have a base knowledge for further training. He will be able to interact with mass spectrometry specialists and ask for the right experiments needed for the project of interest and will be able to interpretate the results, both by qualitative and quantitative point of views.
Assessment criteria of knowledge
The student's ability to explain correctly the main topics presented during the course at the board will be assessed.
Methods:
Teaching methods
Delivery: face to face
Learning activities:
- attending lectures
- participation in seminar
- participation in discussions
- Bibliography search
Attendance: Advised
Teaching methods:
- Lectures
- Seminar
- laboratory
Syllabus
Introduction to mass spectrometry. Ionization techniques. Mass analyzers and filters. Resolution and resolving power in mass spectrometry. Accurate mass measurements and molecular formulae of organic compounds. Tandem mass spectrometry. Coupling of mass spectrometry to chromatographic separation techniques. Qualitative and quantitative analysis. Biological mass spectrometry. Guidelines to the interpretation of mass spectra and fragmentation patterns. Quick insights to modern developments: Ambient ionization, Ion Mobility, Microfluidic techniques, etc.
Bibliography
Recomended reading include:
de Hoffmann, Stroobant – “Mass Spectrometry”, 3a Edizione, Wiley, 2009
Cappiello (Ed) – “Advances in LC-MS Instrumentation”, Elsevier, 2007
Updated: 14/11/2016 17:27
