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PHYSIO-PATHOLOGY
VINCENZO DE TATA
Academic year2023/24
CourseBIOTECHNOLOGIES AND APPLIED ARTIFICIAL INTELLIGENCE FOR HEALTH
Code023FE
Credits6
PeriodSemester 2
LanguageEnglish

ModulesAreaTypeHoursTeacher(s)
PHYSIOBIO/09,MED/04LEZIONI48
ROSARIO AMATO unimap
VINCENZO DE TATA unimap
Syllabus not available in selected language
Learning outcomes
Knowledge

The course provides the study of cellular and molecular mechanisms underlying the maintenance of the homeostatic balance in tissues and organs and their alterations in disease conditions. By the end of the course, students will have acquired knowledge about the biological basis of tissues and organ function in physiological conditions to be compared with pathological mechanisms characterizing the onset and progression of diseases.  

 

Assessment criteria of knowledge

The knowledge acquired by the student during the course will be verified at the time of the final exam.

Skills

Students will be able to conduct research and analysis of sources to be applied either to basic and translational research or to the clinical practice in the context of the health system.

Assessment criteria of skills

The knowledge acquired by the student during the course will be verified at the time of the final exam.

Behaviors

Students will be able to manage the responsibility of managing a team project. Students will acquire accuracy and precision when collecting and analysing experimental data. 

Assessment criteria of behaviors

The knowledge acquired by the student during the course will be verified at the time of the final exam.

Prerequisites

Students are required to have a basic knowledge of Physiology, Biochemestry, Molecular Biology and Immunology. 

Syllabus
  • Introduction to Physio-Pathology
  • Functional porperties of blood
  • Heart physiology: Cardiac potentials
  • Heart physiology: Excitation-contraction coupling
  • Hemodynamic and capillary exchange. 
  • Short- and long-term regulation of blood pressure.
  • Introduction to the endocrine physiology.
  • The Hypothalamic-Pituitary axis.
  • Thyroid and parathyroids. 
  • Control of calcium homeostasis.
  • Control of glucose homeostasis 
  • Pathophysiology of myocardial infarction.
  • Atherosclerosis as an inflammatory disease.
  •  Morphological alterations (necrosis)Ischemia/reperfusion injury. Thrombosis. Virchow's triad.
  • Arterial and venous thrombi. Embolism. Pulmonary embolism. Decompression sickness. Fat embolism.
  • General physiopathology of the red blood cells.
  • Pathophysiology of leukocytes.
  • Pathophysiology of shock.
  • Pathophysiology of the endocrine system. Pituitary pathophysiology. Pituitary dwarfism. Gigantism and acromegaly.
  • Pathophysiology of the thyroid. 
  • Pathophysiology of diabetes mellitus.
Bibliography

Slides and additional material shared with students 

Assessment methods

The exam is made up of an interview (about 30 minutes) between the candidate and the lecturers.

The test will not have a positive outcome if the candidate shows an inability to express him/herself in a clear manner using the correct terminology, if the candidate does not respond sufficiently to questions regarding the most fundamental part of the course, or if the candidate repeatedly demonstrates an incapacity to relate and link parts of the programme.

Notes

The examination committee is composed by: 

Head of commitee: Vincenzo De Tata

Vice-Head of committee: Rosario Amato

Supplemental members: Massimo Dal Monte, Giovanni Casini, Maurizio Cammalleri, Dominga Lapi, Michela Novelli and Alessandro Corti

 

Updated: 13/09/2023 11:13